After a mysterious woman arranges an appointment at Baker Street, Sherlock Holmes finds himself thrust into an inquiry with far-reaching implications. What begins as a simple investigation into a missing person soon morphs into a mystery that threatens to have unprecedented turmoil for both the British Empire and perhaps the rest of the world. As a result, Holmes and Watson soon find themselves racing to uncover the fiendish plot that might well spell death for hundreds of thousands and untold suffering for millions more.
Taxed to the limit, the Great Detective and his Boswell follow the slightest of clues as they journey to Manchester and then back to the London docks and a stately townhouse in St. James. With danger seemingly lurking at each stop along the way, Holmes soon discovers that every thread he is following has been carefully cut by his unseen adversary.
With time running out and the fate of England hanging in the balance, Holmes is forced to surround himself with a ragtag assortment of reinforcements as he prepares for a showdown with a nemesis who has shown himself to be both cunning and unscrupulous. Out of options, Holmes decides to press the issue and hope that he is finally one step ahead of his foe.
